The chair conformation of C-methylcalix[4]resorcinarene in a novel, stepped, supramolecular framework

The previously unobserved chair conformation of C-methylcalix[4]resorcinarene has been found in three different supramolecular solids, prepared by hydrothermal synthesis. The existence of the chair, crown and flattened cone conformations of C-methylcalix[4]resorcinarene demonstrates the dependence of the molecular conformation upon the templating molecules, and upon the specifics of the crystallization process. A novel, three-dimensional framework capable of including guest molecules is described.